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Filtered Search Results
eMolecules 371935-74-9 | PI-103 | AstaTech | MFCD11983145 | 348.362 | C19H16N4O3 | 95.000 | Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 | 0.1g | 282977604
PI-103 | AstaTech | 371935-74-9 | MFCD11983145 | 348.362 | C19H16N4O3 | 95.000 | Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1 | 0.1g | 282977604
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Selleck Chemical LLC Dorsomorphin 2HCl
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Dorsomorphin 2HCl is a potent reversible selective AMPK inhibitor with Ki of 109 nM in cell-free assays exhibiting no significant inhibition of several structurally related kinases including ZAPK SYK PKC PKA and JAK3 Also inhibits type BMP receptor activity Dorsomorphin induces autophagy in cancer cell line
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Medchemexpress LLC Pki 14-22 amide,myristoylated | 201422-03-9 | 99.65% | 1209.49 | 5 MG
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Pki 14-22 amide,myristoylated | 201422-03-9 | 99.65% | 1209.49 | 5 MG
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Medchemexpress LLC Derenofylline | 251945-92-3 | 99.9% | 308.38 | 50 MG
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Derenofylline (SLV 320) is a potent, selective, and orally active adenosine A1 receptor antagonist. It exhibits Ki values of 1 nM for human A1, 200 nM for A3, and 398 nM for A2A receptors. This compound suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats. It has also shown to inhibit TGF-β1-induced myofibroblast transformation in vitro and reduce myocardial fibrosis in vivo.
- Potent, selective, and orally active adenosine A1 receptor antagonist
- Suppresses cardiac fibrosis
- Attenuates albuminuria
- Inhibits TGF-β1-induced myofibroblast transformation (in vitro)
- Reduces myocardial fibrosis in 5/6 nephrectomy rats (in vivo)
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Medchemexpress LLC SSD114 hydrochloride | 2319790-02-6 | MFCD31619246 | 99.1% | 387.83 | C18H21ClF3N3O | 25 MG
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SSD114 hydrochloride is a small-molecule positive allosteric modulator of the GABAB receptor intended for in vitro and in vivo research use only.
- Acts as a GABAB receptor positive allosteric modulator for pharmacological studies.
- High purity suitable for research applications.
- Solid, white to off-white appearance for ease of handling.
- Available in multiple small-scale quantities for experimental flexibility.
- Stable under recommended storage conditions to preserve compound integrity.
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Medchemexpress LLC PKI-166 10mg | 187724-61-4 | 330.38 | C20H18N4O | 10 MG
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PKI-166 is a potent, selective, and orally bioavailable epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with a reported IC50 of 0.7 nM. It is provided for research use only and has molecular formula C20H18N4O and high purity by HPLC.
- Potent EGFR kinase inhibition (IC50 ≈ 0.7 nM).
- High chemical purity (≥98% by HPLC).
- Suitable for in vitro and in vivo research applications.
- Orally bioavailable in preclinical studies.
- Well-characterized molecular properties for experimental reproducibility.
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Medchemexpress LLC HY-10182 100mg , CHIR-99021 CT99021 CAS:252917-06-9 Purity:98%
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Medchemexpress, HY-10182 100mg CHIR-99021 CT99021 CAS:252917-06-9 Formula:C22H18Cl2N8 IC50: 10 nM/6.7 nM (GSK-3α/β) Purity:98% CHIR-99021 is a GSK-3α/β inhibitor with IC 50 of 10 nM/6.7 nM; > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-101420 5mg Medchemexpress, VUF10460 CAS:1028327-66-3 Purity:>98%
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Medchemexpress, HY-101420 5mg VUF10460 CAS:1028327-66-3 VUF10460 is a non-imidazole histamine H4 receptor agonist; binds to rat H4 receptor with a pK i of 7.46. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC BAY 61-3606 732983-37-8 5mg
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BAY 61-3606 (CAS 732983-37-8) is a selective orally bioavailable inhibitor of spleen tyrosine kinase (SYK) displaying an IC50 of 10 nM and a Ki of 7 5 nM for SYK by competitively binding ATP This compound shows minimal activity against other tyrosine kinases such as Src Fyn Lyn Btk and Itk at concentrations up to 4 7 M BAY 61-3606 suppresses Fc RI-mediated degranulation and mediator release in mast cells and basophils as well as Fc R-driven responses in macrophages and neutrophils In preclinical models BAY 61-3606 attenuates inflammatory cell functions and reduces allergic and asthmatic responses supporting its utility in investigating SYK-mediated signaling and inflammation
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eMolecules 1346156-91-9 | TERT-BUTYL 3-BROMO-2-FORMYL-1H-INDOLE-1-CARBOXYLATE | MFCD24471460 | 1g
ChemScene | (3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl)methanol | 100mg | 572167053 | CS-0017743 | 1627924-18-8 | MFCD29918655 | 308.119 | C9H13IN2O2
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Apexbio Technology LLC PKI-402 5MG
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PKI-402 5MG APEXBIO TECHNOLOGIES
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Medchemexpress LLC 4-pyrimidinemethanol | 33581-98-5 | MFCD03789625 | ≥97.0% | 110.11 | C5H6N2O | 500 MG
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Pyrimidin-4-yl-methanol (4-pyrimidinemethanol) is a small-molecule synthetic intermediate used in medicinal and pharmaceutical chemistry for constructing pyrimidine-containing compounds. It is supplied as a solid (light yellow to yellow), with molecular formula C5H6N2O, molecular weight 110.11, CAS 33581-98-5, and typical purity ≥97%. Available in multiple pack sizes for research and synthesis.
- Useful intermediate for synthesis of pyrimidine derivatives.
- High reported purity suitable for research and development.
- Well-defined molecular formula and molecular weight for formulation and analysis.
- Supplied as a solid for straightforward handling and storage.
- Available in multiple pack sizes to support different scales of work.
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eMolecules 854890-84-9 | 1-(2,5-Dibromophenyl)thiourea | Combi-Blocks | MFCD14673413 | 310.010 | C7H6Br2N2S | 98.000 | NC(=S)Nc1cc(Br)ccc1Br | 1g | 117531798
1-(2,5-Dibromophenyl)thiourea | Combi-Blocks | 854890-84-9 | MFCD14673413 | 310.010 | C7H6Br2N2S | 98.000 | NC(=S)Nc1cc(Br)ccc1Br | 1g | 117531798
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Medchemexpress LLC Phenyl 6-(3-methoxy-2-(4-(trifluoromethyl)phenyl)benzoylamino)-3,4-dihydroisoquinoline-2-carboxylate | 913541-47-6 | MFCD28502203 | 99.0% | 546.54 | C31H25F3N2O4 | 50 MG
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SLX-4090 is an orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor (IC50 8.0 nM) used as a research reagent in dyslipidemia and lipid metabolism studies. It is supplied as a purified solid and is available in solution formats suitable for in vitro and in vivo assays.
- High potency MTP inhibition (IC50 ~8.0 nM).
- Enterocytic-specific activity useful for targeted lipid studies.
- High purity (about 98.97%) for reproducible results.
- Available as solid and DMSO solution formats for assay flexibility.
- Suitable for dyslipidemia and lipid metabolism research models.
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eMolecules 50739-76-9 | (2-Amino-3,5-dibromophenyl)methanol | Combi-Blocks | MFCD06202693 | 280.947 | C7H7Br2NO | 95.000 | Nc1c(Br)cc(Br)cc1CO | 1g | 439374801
(2-Amino-3,5-dibromophenyl)methanol | Combi-Blocks | 50739-76-9 | MFCD06202693 | 280.947 | C7H7Br2NO | 95.000 | Nc1c(Br)cc(Br)cc1CO | 1g | 439374801
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